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- Thi Ngoc Nhu Phan
Thi Ngoc Nhu Phan
Associate Senior Lecturer
Department of Chemistry & Molecular BiologyAbout Thi Ngoc Nhu Phan
The research within the Phan group is focused on the development and application of mass spectrometry imaging (ToF-SIMS, NanoSIMS, MALDI), super-resolution stimulated emission depletion (STED) microscopy, electron microscopy, and correlative imaging using combinations of these modalities to understand the structural and functional relationship of biomolecules in neural stem cells, neuronal cells and in the brain. Another research topic is the development of novel labelling probes for correlative imaging. The probes enable imaging multiple targeted molecules at micro and nanoscale resolution using the combination of SIMS, fluorescence microscopy, and electron microscopy.
The developed technologies have been applied to the following biological questions:
• Organization of structural lipids at synaptic membrane, and its relation to neuronal activity.
• Targeted molecular imaging of the brain, structural and functional relation in brain activity.
• Molecular turnover in neuronal cells and brain, and correlation to neuro-degeneration.
• Molecular turnover, dynamics and regulation in neural stem cells.
• Stress granule pathway and molecular transition in neuronal cells.
LINKS
Nhu Phan group home page:
TEACHING
KEM070 - Basic Analytical Chemistry
KEM082 - Advanced Analytical Chemistry
KEA310 - Introduction to Analytical Chemistry
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Emmanuel Berlin, Alicia Lork, Martin Bornecrantz, Carl Ernst, Nhu TN Phan
TALANTA - 2024 -
Alicia Lork, Stefania Rabasco, Carl Ernst, Andre Du Toit, Silvio O. Rizzoli, Nhu TN Phan
CHEMICAL SCIENCE - 2024 -
Stefania Rabasco, Alicia Lork, Emmanuel Berlin, Tho D. K. Nguyen, Carl Ernst, Nicolas Locker, Andrew G Ewing, Nhu TN Phan
International Journal of Molecular 91̽»¨s - 2023 -
K. K. Hu, Kim Vo, F. Wang, X. Zhang, Chaoyi Gu, N. Fang, Nhu TN Phan, Andrew G Ewing
Journal of the American Chemical Society - 2023 -
Martin Meschkat, Anna M. Steyer, Marie-Theres Weil, Kathrin Kusch, Olaf Jahn, Lars Piepkorn, Paola Aguei-Gonzalez, Nhu TN Phan, Torben Ruhwedel, Boguslawa Sadowski, Silvio O. Rizzoli, Hauke B. Werner, Hannelore Ehrenreich, Klaus-Armin Nave, Wiebke Moebius
NATURE COMMUNICATIONS - 2022 -
Tho D. K. Nguyen, Lisa J. Mellander, Alicia Lork, Aurélien Thomen, M. Philipsen, M. E. Kurczy, Nhu TN Phan, Andrew G Ewing
Acs Nano - 2022 -
Tho D. K. Nguyen, Alicia Lork, Andrew G Ewing, Nhu TN Phan
Single Cell ‘Omics of Neuronal Cells - 2022 -
A. A. Lork, K. L. L. Vo, Nhu TN Phan
Frontiers in Synaptic Neuroscience - 2022 -
Stefania Rabasco, Tho D. K. Nguyen, Chaoyi Gu, Michael E. Kurczy, Nhu TN Phan, Andrew G Ewing
International Journal of Molecular 91̽»¨s - 2022 -
Ying-Ning Zheng, Tho D. K. Nguyen, Johan Dunevall, Nhu TN Phan, Andrew G Ewing
ACS measurement science Au - 2021 -
Keke Hu, E. Relton, N. Locker, Nhu TN Phan, Andrew G Ewing
Angewandte Chemie - International Edition - 2021 -
Felix Lange, Paola Agüi-Gonzalez, Dietmar Riedel, Nhu TN Phan, Stefan Jakobs, Silvio O. Rizzoli
PLoS ONE - 2021 -
P. Agui-Gonzalez, T. M. Dankovich, S. O. Rizzoli, Nhu TN Phan
Nanomaterials - 2021 -
P. Aguei-Gonzalez, G. B. Bao, M. A. G. de Castro, S. O. Rizzoli, Nhu TN Phan
Acs Chemical Neuroscience - 2021 -
Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Biorxiv preprint - 2020 -
Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
ACS Chemical Neuroscience - 2020 -
Aurélien Thomen, Neda Najafinobar, Florent Penen, Emma Kay, Pratik P. Upadhyay, Xianchan Li, Nhu TN Phan, Per Malmberg, Magnus Klarqvist, Shalini Andersson, Michael E. Kurczy, Andrew G Ewing
ACS nano - 2020 -
Nhu TN Phan, S. O. Rizzoli
Volume Microscopy - 2020 -
Pieter E. Oomen, Mohaddeseh A. Aref, Ibrahim Kaya, Nhu TN Phan, Andrew G Ewing
Analytical Chemistry - 2019 -
P Agüi-Gonzalez, S Jähne, Nhu TN Phan
Journal of Analytical Atomic Spectrometry - 2019 -
K N Richter, C Patzelt, Nhu TN Phan, S O Rizzoli
Scientific Reports - 2019 -
S Kabatas, P Agüi-Gonzalez, K Ann Saal, S Jähne, F Opazo, S O Rizzoli, Nhu TN Phan
Angewandte Chemie - International Edition - 2019 -
S Kabatas, P Agüi-Gonzalez, R Hinrichs, S Jähne, F Opazo, U Diederichsen, S O Rizzoli, Nhu TN Phan
Journal of Analytical Atomic Spectrometry - 2019 -
Mai H. Philipsen, Nhu TN Phan, John S. Fletcher, Per Malmberg, Andrew G Ewing
Acs Chemical Neuroscience - 2018 -
Nhu TN Phan, Xianchan Li, Andrew G Ewing
Nature Reviews Chemistry - 2017 -
Nhu TN Phan, Amir Saeid Mohammadi, Masoumeh Dowlatshahi Pour, Andrew G Ewing
Analytical Chemistry - 2016 -
Amir Saeid Mohammadi, Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Analytical and Bioanalytical Chemistry - 2016 -
Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Analytical Chemistry - 2015 -
Nhu TN Phan
2015 -
Nhu TN Phan, John S. Fletcher, Andrew G Ewing
Reference Module in Chemistry, Molecular 91̽»¨s and Chemical Engineering - 2014 -
Nhu TN Phan, John S. Fletcher, Peter Sjövall, Andrew G Ewing
Surface and Interface Analysis: 19th International Conference on Secondary Ion Mass Spectrometry (SIMS) - 2014 -
Ingela Lanekoff, Nhu TN Phan, C. T. Van Bell, N. Winograd, Peter Sjövall, Andrew G Ewing
Surface and Interface Analysis - 2013 -
Nhu TN Phan, Jörg Hanrieder, Carina Berglund, Andrew G Ewing
Analytical Chemistry - 2013 -
Jörg Hanrieder, Nhu TN Phan, Michael E. Kurczy, Andrew G Ewing
ACS chemical neuroscience - 2013 -
E Carina Berglund, Monique A Makos, Jacqueline Keighron, Nhu TN Phan, Michael L Heien, Andrew G Ewing
ACS chemical neuroscience - 2013