91̽»¨

Research summary

Our research seek to identify biomarkers of response to new targeted therapies and immunotherapies. We are making personalized animal models, so called PDX models or Avatar mice. These are used to test drugs as well as further humanization for use in immune oncology research.

The research has generated the framework of starting the Sahlgrenska Translational Melanoma Group (SATMEG), consisting of basic researchers and clinical investigators working together to devise new therapies against melanoma.

Group members at SCCR

Lead:
Jonas Nilsson, PhD, Group leader at Sahlgrenska Center for Cancer Research and Professor of Experimental Cancer Surgery

Senior Research Fellows:
Lisa Nilsson, PhD, Senior staff scientist
Lars Ny, MD/PhD, Associate professor, oncologist
Axel Nelson, MD/PhD, Postdoctoral fellow
Maria Öberg, PhD, Postdoctoral fellow
Rebecca Riise, PhD, Researcher

Technical staff:
Carina Karlsson, Biomedical Scientist
Sofia Stenqvist, Animal technician

Affiliated members:
Sahlgrenska Translational Melanoma Group (SATMEG)

Selected publications

1. 
   Ny L, Jespersen H, Karlsson J, Alsén S, Filges S, All-Eriksson C, Andersson B, Carneiro A, Helgadottir H, Levin M, Ljuslinder I, Olofsson Bagge R, Sah V, Stierner U, StÃ¥hlberg A, Ullenhag G, Nilsson LM, Nilsson JA. Nature communications, 2021, epub.
    
2. 
   Karlsson J, Nilsson LM, Mitra S, Alsén S, Shelke GS, Sah VR, Forsberg EMV, Stierner U, All-Eriksson C, Einarsdottir BO, Jespersen H, Ny L, Lindnér P, Larsson E, Olofsson Bagge R, Nilsson JA. Nature communications, 2020, 11:1894
    
3. 
   Ny L, Rizzo LY, Belgrano V, Karlsson J, Jespersen J, Carstam L, Olofsson Bagge R, Nilsson LM, Nilsson JA. Annals of Oncology, 2020, 31:266-273
    
4. 
   Hofving T, Karlsson J, Nilsson, O, Nilsson JA. Nature Genetics, 2019, 51:1426-1427
    
5. 
   Forsberg EM, Lindberg MF, Jespersen H, Alsén S, Olofsson Bagge R, Donia M, Svane IM, Nilsson O, Ny L, Nilsson LM, Nilsson JA. Cancer Res. 2019
    
6. 
   Jespersen H, Lindberg MF, Donia M, Söderberg EMV, Andersen R, Keller U, Ny L, Svane IM, Nilsson LM, Nilsson JA. Nature communications. 2017; 8(1):707. 
    
7. 
   Bhadury J, Nilsson LM, Muralidharan SV, Green LC, Li Z, Gesner EM, Hansen HC, Keller UB, McLure KG, Nilsson JA. Proceedings of the National Academy of 91̽»¨s of the United States of America. 2014; 111(26):E2721-30.
    
8. 
   Höglund A, Nilsson LM, Muralidharan SV, Hasvold LA, Merta P, Rudelius M, Nikolova V, Keller U, Nilsson JA. Clin Cancer Res. 2011; 17(22):7067-79. 
    
9. 
   Höglund A, Nilsson LM, Forshell LP, Maclean KH, Nilsson JA. Blood. 2009; 113(18):4281-8.
    
10. 
    Nilsson JA, Keller UB, Baudino TA, Yang C, Norton S, Old JA, Nilsson LM, Neale G, Kramer DL, Porter CW, Cleveland JL. Cancer cell. 2005; 7(5):433-44.